Exploring Chronic Oxidative Stress Linked to Dental Procedures

When examining the potential connection between dental procedures and long-term inflammatory responses, several peer-reviewed studies offer important clinical insight. Research has explored how materials used in root canal therapy and metal-based dental implants may, in certain situations, contribute to localized tissue reactions, chronic irritation, or oxidative stress. While these findings do not suggest that such outcomes are common, they highlight the importance of understanding how dental materials interact with biological systems over time.
The following studies provide case-based evidence and clinical observations related to chronic inflammation, fungal infections, and oxidative processes associated with dental treatments. Together, they help frame ongoing discussions around chronic oxidative stress of dental origin, particularly in relation to root canals and metal implants.
- A Case of Coexistent Fungal Rhinosinusitis and Actinomycosis Caused by Gutta-Percha Points Extruded Into the Maxillary Sinus
- Risk of maxillary fungus ball in patients with endodontic treatment on maxillary teeth: a case-control study
- Dental aspects of solitary maxillary sinus aspergillosis. A clinical, microanalytical and experimental study
- Aspergillus mycetoma of the maxillary sinus secondary to overfilling of a root canal
